Following the pandemic, many people are finding it difficult to reunite with their social groups. Social isolation and loneliness are associated with behaviors that negatively impact cardiovascular and brain health, such as lower levels of self-reported physical activity, low nutritional intake, and a more sedentary lifestyle. Multiple large studies found significant associations between loneliness and a higher likelihood of smoking and other addictive habits. Taking charge of your mental health to overcome isolation and loneliness will make life worth living again, and it might just save your life.